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(S)-3,4-DCPG (UBP1109)

Names

[ CAS No. ]:
201730-11-2

[ Name ]:
(S)-3,4-DCPG (UBP1109)

[Synonym ]:
hms3267l19

Biological Activity

[Description]:

(S)-3,4-DCPG is a selective agonist of metabotropic glutamate receptor 8a (mGluR8a) with an EC50 of 31 nM in AV12-664 cells expressing human mGluR8[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR
Research Areas >> Neurological Disease

[Target]

hmGluR8a:31 nM (EC50)


[References]

[1]. Thomas NK, et al. (S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord. Neuropharmacology. 2001 Mar;40(3):311-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H9NO6

[ Molecular Weight ]:
239.18200

[ Exact Mass ]:
239.04300

[ PSA ]:
137.92000

[ LogP ]:
0.86770

[ Storage condition ]:
Desiccate at RT


Related Compounds