UAA crosslinker 1 hydrochloride

Names

[ CAS No. ]:
1994331-17-7

[ Name ]:
UAA crosslinker 1 hydrochloride

Biological Activity

[Description]:

UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases[1].

[Related Catalog]:

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Research Areas >> Others

[References]

[1]. Kofoed C, et al. Semisynthesis of an Active Enzyme by Quantitative Click Ligation. Bioconjug Chem. 2019 Apr 17;30(4):1169-1174.

Chemical & Physical Properties

[ Molecular Formula ]:
C9H18ClN5O4

[ Molecular Weight ]:
295.72

Related Compounds