Metoxuran
Names
[ CAS No. ]:
19937-59-8
[ Name ]:
Metoxuran
[Synonym ]:
Dosaflo
N’-(3-chloro-4-methoxyphenyl)-N,N-dimethylurea
Sulerex
N'-(3-Chloro-4-methoxyphenyl)-N,N-dimethylurea
Urea, N'-(3-chloro-4-methoxyphenyl)-N,N-dimethyl-
Metoxuron solution
Purivel
3-(3-Chloro-4-methoxyphenyl)-1,1-dimethylurea
Dosanex FL
MFCD00055444
Metoxuran
EINECS 243-433-2
Dosagran
Deftor
Metoxuron
Dosanex
Dosanex MG
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
391.6±42.0 °C at 760 mmHg
[ Melting Point ]:
124-127ºC
[ Molecular Formula ]:
C10H13ClN2O2
[ Molecular Weight ]:
228.675
[ Flash Point ]:
190.6±27.9 °C
[ Exact Mass ]:
228.066559
[ PSA ]:
41.57000
[ LogP ]:
1.80
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.578
[ Storage condition ]:
APPROX 4°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS5775000
- CHEMICAL NAME :
- Urea, N'-(3-chloro-4-methoxyphenyl)-N,N-dimethyl-
- CAS REGISTRY NUMBER :
- 19937-59-8
- BEILSTEIN REFERENCE NO. :
- 2128284
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C10-H13-Cl-N2-O2
- MOLECULAR WEIGHT :
- 228.70
- WISWESSER LINE NOTATION :
- 1OR BG DMVN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2542 mg/kg
- TOXIC EFFECTS :
- Endocrine - other changes Blood - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2558 mg/kg/43W-I
- TOXIC EFFECTS :
- Liver - other changes Endocrine - hyperglycemia Blood - methemoglobinemia-carboxyhemoglobin
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,353,1978
Safety Information
[ Symbol ]:
GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H410
[ Precautionary Statements ]:
P273-P501
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;F: Flammable;N: Dangerous for the environment;
[ Risk Phrases ]:
R50/53
[ Safety Phrases ]:
60-61-36-26-16
[ RIDADR ]:
UN3077 9
[ RTECS ]:
YS5775000
[ Hazard Class ]:
9.0
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Gig. Sanit. (2) , 13-5, (1982)
[Effect of dosanex on the immunologic reactions in animals].
Gig. Sanit. (2) , 85-6, (1983)
Structure-activity relationship (SAR) studies of benzoxazinones, their degradation products, and analogues. Phytotoxicity on problematic weeds Avena fatua L. and Lolium rigidum Gaud.
J. Agric. Food Chem. 54(4) , 1040-8, (2006)
Avena fatua L. (wild oat) and Lolium rigidum Gaud. (rigid ryegrass) are highly problematic weeds affecting a wide variety of cereal crops worldwide. The fact that both of these weeds have developed re...