Bakkenolide A

Names

[ CAS No. ]:
19906-72-0

[ Name ]:
Bakkenolide A

[Synonym ]:
Bakkenolide A
Spiro[furan-3(2H),2'-[2H]inden]-2-one, decahydro-3'a,4'-dimethyl-4-methylene-, (3R,3a'R,4'S,7a'R)-
Fukinanolid
Bakkenolid A
(3R,3a'R,4'S,7a'R)-3a',4'-Dimethyl-4-methylenedecahydrospiro[furan-3,2'-inden]-2-one
FUKINANOLIDE

Biological Activity

[Description]:

Bakkenolide A is a natural product extracted from Petasites tricholobus. Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Zhang L, et al. Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways. Biomed Pharmacother. 2016 Oct;83:958-966.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
360.7±31.0 °C at 760 mmHg

[ Melting Point ]:
80-81 °C

[ Molecular Formula ]:
C₁₅H₂₂O₂

[ Molecular Weight ]:
234.334

[ Flash Point ]:
150.7±22.2 °C

[ Exact Mass ]:
234.161987

[ PSA ]:
26.30000

[ LogP ]:
3.67

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.518

Related Compounds

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