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19906-72-0

19906-72-0 structure
19906-72-0 structure
  • Name: Bakkenolide A
  • Chemical Name: (2R,3aR,7S,7aR)-7,7a-dimethyl-4'-methylidenespiro[3,3a,4,5,6,7-hexahydro-1H-indene-2,3'-oxolane]-2'-one
  • CAS Number: 19906-72-0
  • Molecular Formula: C15H22O2
  • Molecular Weight: 234.334
  • Catalog: Research Areas Cancer
  • Create Date: 2018-03-06 08:00:00
  • Modify Date: 2024-01-08 10:49:00
  • Bakkenolide A is a natural product extracted from Petasites tricholobus. Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways[1].

Name (2R,3aR,7S,7aR)-7,7a-dimethyl-4'-methylidenespiro[3,3a,4,5,6,7-hexahydro-1H-indene-2,3'-oxolane]-2'-one
Synonyms Bakkenolide A
Spiro[furan-3(2H),2'-[2H]inden]-2-one, decahydro-3'a,4'-dimethyl-4-methylene-, (3R,3a'R,4'S,7a'R)-
Fukinanolid
Bakkenolid A
(3R,3a'R,4'S,7a'R)-3a',4'-Dimethyl-4-methylenedecahydrospiro[furan-3,2'-inden]-2-one
FUKINANOLIDE
Description Bakkenolide A is a natural product extracted from Petasites tricholobus. Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways[1].
Related Catalog
References

[1]. Zhang L, et al. Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways. Biomed Pharmacother. 2016 Oct;83:958-966.

Density 1.1±0.1 g/cm3
Boiling Point 360.7±31.0 °C at 760 mmHg
Melting Point 80-81 °C
Molecular Formula C15H22O2
Molecular Weight 234.334
Flash Point 150.7±22.2 °C
Exact Mass 234.161987
PSA 26.30000
LogP 3.67
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.518