(R)-FT671

Names

[ CAS No. ]:
1959551-27-9

[ Name ]:
(R)-FT671

Biological Activity

[Description]:

(R)-FT671 is the R-isomer of FT671. FT671 is a potent, non-covalent and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Turnbull AP, et al. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017 Oct 26;550(7677):481-486.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₃F₄N₇O₃

[ Molecular Weight ]:
533.48

Related Compounds

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