dBET23

Names

[ CAS No. ]:
1957234-83-1

[ Name ]:
dBET23

Biological Activity

[Description]:

dBET23 is a BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=50 nM) in cellular degradation assays.

[References]

References 1. Nowak RP, et al. Nat Chem Biol. 2018 Jun 11. doi: 10.1038/s41589-018-0055-y. View Related Products by Target PROTAC

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₃H₄₅ClN₈O₉S

[ Molecular Weight ]:
885.39

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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