Fosclevudine alafenamide

Names

[ CAS No. ]:
1951476-79-1

[ Name ]:
Fosclevudine alafenamide

Biological Activity

[Description]:

Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent with an EC50 of 1.71 μM against HBV[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> HBV

[Target]

EC50: 1.71 μM (HBV)[1]

[In Vitro]

Fosclevudine alafenamide (Compound EIDD-02173) shows cytotoxicity against CEM, A204, IEC-6 and H9c cells[1]. Cell Cytotoxicity Assay[1] Cell Line: CEM, A204, IEC-6, H9c Concentration: 0-400 μM Incubation Time: 6 days Result: Showed cytotoxicity with CC50 values of 140, 330, 307 and 344 μM against CEM, A204, IEC-6 and H9c cells, respectively.

[References]

[1]. Abel De La Rosa, et al. Phosphoramidates for the treatment of hepatitis b virus. WO2017223421A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₉FN₃O₉P

[ Molecular Weight ]:
529.45

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.