Name | Fosclevudine alafenamide |
---|
Description | Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent with an EC50 of 1.71 μM against HBV[1]. |
---|---|
Related Catalog | |
Target |
EC50: 1.71 μM (HBV)[1] |
In Vitro | Fosclevudine alafenamide (Compound EIDD-02173) shows cytotoxicity against CEM, A204, IEC-6 and H9c cells[1]. Cell Cytotoxicity Assay[1] Cell Line: CEM, A204, IEC-6, H9c Concentration: 0-400 μM Incubation Time: 6 days Result: Showed cytotoxicity with CC50 values of 140, 330, 307 and 344 μM against CEM, A204, IEC-6 and H9c cells, respectively. |
References |
[1]. Abel De La Rosa, et al. Phosphoramidates for the treatment of hepatitis b virus. WO2017223421A1. |
Molecular Formula | C22H29FN3O9P |
---|---|
Molecular Weight | 529.45 |