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GaTx2

Names

[ CAS No. ]:
194665-85-5

[ Name ]:
GaTx2

Biological Activity

[Description]:

GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent KD of ∼20 pM. GaTx2 is a peptide toxin inhibitor from Leiurus quinquestriatus hebraeus venom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[Target]

Kd: 20 pM (ClC-2 channel)[1]


[References]

[1]. Christopher H Thompson, et al. Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels.J Biol Chem

Chemical & Physical Properties

[ Molecular Formula ]:
C125H199N39O47S6

[ Molecular Weight ]:
3192.54

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds

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