ω-Hexatoxin-Hv1a

Names

[ CAS No. ]:
193981-10-1

[ Name ]:
ω-Hexatoxin-Hv1a

Biological Activity

[Description]:

ω-Hexatoxin-Hv1a is a neurotoxin that can be isolated from the venom spider (Hadronyche versuta).ω-Hexatoxin-Hv1a blocks voltage-gated calcium channels[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel
Research Areas >> Neurological Disease

[References]

[1]. Powell ME, et al. Demonstrating the potential of a novel spider venom-based biopesticide for target-specific control of the small hive beetle, a serious pest of the European honeybee. J Pest Sci (2004). 2020;93(1):391-402.  

[2]. Yang S, et al. Effect of insecticidal fusion proteins containing spider toxins targeting sodium and calcium ion channels on pyrethroid-resistant strains of peach-potato aphid (Myzus persicae). Pest Manag Sci. 2015 Jul;71(7):951-6.  

Chemical & Physical Properties

[ Molecular Formula ]:
C162H247N49O61S6

[ Molecular Weight ]:
4049.38

Related Compounds

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