1,1'-Ethyne-1,2-diyldi(2H5)benzene

Names

[ CAS No. ]:
19339-46-9

[ Name ]:
1,1'-Ethyne-1,2-diyldi(2H5)benzene

[Synonym ]:
Benzene-d, 1,1'-(1,2-ethynediyl)bis-
Tolan-d10
1,1'-(1,2-Ethynediyl)di(H)benzene
1,1'-Ethyne-1,2-diyldi(H)benzene
bis-pentadeuteriophenyl-ethyne
MFCD01074007
d10-diphenylacetylene
Diphenylacetylene-d10

Biological Activity

[Description]:

1,2-Diphenylethyne-d10 is the deuterium labeled 1,2-Diphenylethyne[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
300.0±11.0 °C at 760 mmHg

[ Melting Point ]:
58-60ºC(lit.)

[ Molecular Formula ]:
C14D10

[ Molecular Weight ]:
188.291

[ Flash Point ]:
126.0±13.4 °C

[ Exact Mass ]:
188.141022

[ LogP ]:
4.78

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.623

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Related Compounds