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Moxifloxacin hydrochloride monohydrate

Names

[ CAS No. ]:
192927-63-2

[ Name ]:
Moxifloxacin hydrochloride monohydrate

[Synonym ]:
Actira
Moxifloxacin hydrochloride monohydrate
UNII-B8956S8609
1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride hydrate
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-, hydrochloride, hydrate (1:1:1)

Biological Activity

[Description]:

Moxifloxacin (BAY 12-8039) hydrochloride monohydrate is an orally active bacterial inhibitor that is effective against Streptococcus pneumoniae. Moxifloxacin hydrochloride monohydrate can be used in tuberculosis research[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Pestova E, et al. Intracellular targets of moxifloxacin: a comparison with other fluoroquinolones. J Antimicrob Chemother. 2000 May;45(5):583-90.  

[2]. Miyazaki E, et al. Moxifloxacin (BAY12-8039), a new 8-methoxyquinolone, is active in a mouse model of tuberculosis. Antimicrob Agents Chemother. 1999 Jan;43(1):85-9.  

Chemical & Physical Properties

[ Melting Point ]:
243-246°C dec.

[ Molecular Formula ]:
C21H27ClFN3O5

[ Molecular Weight ]:
455.91

[ Exact Mass ]:
455.162323

[ PSA ]:
93.03000

[ LogP ]:
3.50200

[ Vapour Pressure ]:
4.56E-17mmHg at 25°C

[ Storage condition ]:
-20°C Freezer

Safety Information

[ RTECS ]:
VB1983750

Precursor & DownStream

Precursor

DownStream

Related Compounds