12-Hydroxymyricanone

Names

[ CAS No. ]:
191999-68-5

[ Name ]:
12-Hydroxymyricanone

[Synonym ]:
Tricyclo[12.3.1.12,6]nonadeca-1(18),2,4,6(19),14,16-hexaen-9-one, 3,8,15-trihydroxy-16,17-dimethoxy-
3,8,15-Trihydroxy-16,17-dimethoxytricyclo[12.3.1.12,6]nonadeca-1(18),2(19),3,5,14,16-hexaen-9-one

Biological Activity

[Description]:

12-Hydroxymyricanone is a nature product that could be isolated from the roots of Myrica nana. 12-Hydroxymyricanone inhibits the release of nitric oxide with an IC50 value of 30.19 μM[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

12-Hydroxymyricanone (compound 8; 0-100 μM) 抑制 Lipopolysaccharides (HY-D1056) 激活的腹膜巨噬细胞中的一氧化氮释放[1]。

[References]

[1]. Wang J, et, al. Cyclic diarylheptanoids from Myrica nana inhibiting nitric oxide release. Bioorg Med Chem. 2008 Sep 15;16(18):8510-5.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
628.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₄O₆

[ Molecular Weight ]:
372.412

[ Flash Point ]:
222.9±25.0 °C

[ Exact Mass ]:
372.157288

[ LogP ]:
2.31

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.600

Related Compounds

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