Solasonine

Names

[ CAS No. ]:
19121-58-5

[ Name ]:
Solasonine

[Synonym ]:
α-Solasonine
PURAPURIN
Solasoonine
Purapurine
SOLANINE S
Solanine-S
SOLASONIN
(3β,22α,25R)-Spirosol-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->;3)]-β-D-galactopyranoside
SOLASODAMINE
(3b,22a,25R)-Spirosol-5-en-3-yl O-6-Deoxy-a-L-mannopyranosyl(1®2)-O-[b-D-glucopyranosyl(1®3)]-b-D-galactopyranoside
β-D-Galactopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->3)]-
UNII:TR60638HXL
SOLANCARPIN

Biological Activity

[Description]:

Solasonine is a steroidal glycoalkaloid isolated from Solanum nigrum L.. Solasonine has cytotoxicity to human gastric cancer cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Ding X, et al. Purification, antitumor activity in vitro of steroidal glycoalkaloids from black nightshade (Solanum nigrum L.). Food Chem. 2013 Nov 15;141(2):1181-6.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Melting Point ]:
301-303℃

[ Molecular Formula ]:
C₄₅H₇₃NO₁₆

[ Molecular Weight ]:
884.058

[ Exact Mass ]:
883.492920

[ PSA ]:
258.71000

[ LogP ]:
4.35

[ Index of Refraction ]:
1.628

[ Storage condition ]:
2-8C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WF1450000

CHEMICAL NAME :: Solasonine

CAS REGISTRY NUMBER :: 19121-58-5

LAST UPDATED :: 198207

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C45-H73-N-O16

MOLECULAR WEIGHT :: 884.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 77300 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 15,285,1977

Precursor & DownStream

Precursor

DownStream

Related Compounds

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