Remdesivir nucleoside monophosphate

Names

[ CAS No. ]:
1911578-74-9

[ Name ]:
Remdesivir nucleoside monophosphate

Biological Activity

[Description]:

Remdesivir nucleoside monophosphate is a metabolite of Remdesivir[1]. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV[2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

Signaling Pathways >> Anti-infection >> SARS-CoV

[References]

[1]. Byoung Kwon Chun, et al. or treating filoviridae virus infections. US20160122374.

[2]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₄N₅O₇P

[ Molecular Weight ]:
371.24

Related Compounds

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