Isocupressic acid

Names

[ CAS No. ]:
1909-91-7

[ Name ]:
Isocupressic acid

[Synonym ]:
1-Naphthalenecarboxylic acid, decahydro-5-[(3E)-5-hydroxy-3-methyl-3-penten-1-yl]-1,4a-dimethyl-6-methylene-, (1S,4aR,5S,8aR)-
15-hydroxyisolongifolane
(1S,4aR,5S,8aR)-5-[(3E)-5-Hydroxy-3-methyl-3-penten-1-yl]-1,4a-dimethyl-6-methylenedecahydro-1-naphthalenecarboxylic acid
Isocupressic acid
3-isolongifolol

Biological Activity

[Description]:

Isocupressic acid ((+)-Isocupressic acid) is an abortifacient compound[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Isocupressic acid (1-1000 ng/mL; 4 h) inhibits basal and ovine luteinizing hormone (oLH) stimulating secretion of progesterone in bovine luteal cells without cell death[1]. Isocupressic acid inhibits progesterone production by blocking oLH and cAMP actions at the cellular level of luteal cells[1].

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
454.2±38.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₂O₃

[ Molecular Weight ]:
320.466

[ Flash Point ]:
242.6±23.3 °C

[ Exact Mass ]:
320.235138

[ PSA ]:
57.53000

[ LogP ]:
5.51

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.528

Related Compounds

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