(3,4-Dimethoxyphenyl)(2H2)acetic acid

Names

[ CAS No. ]:
19031-58-4

[ Name ]:
(3,4-Dimethoxyphenyl)(2H2)acetic acid

[Synonym ]:
(3,4-Dimethoxyphenyl)(H)acetic acid
Benzeneacetic-d acid, 3,4-dimethoxy-

Biological Activity

[Description]:

3,4-Dimethoxyphenylacetic acid-d2 is the deuterium labeled 3,4-Dimethoxyphenylacetic acid[1]. 3,4-Dimethoxyphenylacetic acid is a building block in the chemical synthesis[2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Frederick A, et al. Occurrence of 3,4-Dimethoxyphenylacetic Acid in Urines of Normal and Schizophrenic Individuals. Nature volume211, pages606–608 (06 August 1966)

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
331.4±27.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H10D2O4

[ Molecular Weight ]:
198.212

[ Flash Point ]:
130.2±17.2 °C

[ Exact Mass ]:
198.086105

[ PSA ]:
55.76000

[ LogP ]:
1.24

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.527

Related Compounds