Hexachloropropene
Names
[ CAS No. ]:
1888-71-7
[ Name ]:
Hexachloropropene
[Synonym ]:
1,1,2,3,3,3-Hexachloro-1-propene
MFCD00000835
Hexachloropropene
Perchloropropylene
2-chloro-1,1,3,3,3-pentachloropropene
EINECS 217-560-9
RCRA waste no. U243
1,1,2,3,3,3-hexachloroprop-1-ene
PERCHLOROPROPENE
Hexachloropropylene
Hexachlorpropylen
RCRA waste number U243
Propene,hexachloro
1-Propene,1,1,2,3,3,3-hexachloro
Hexachlor-propen
1-Propene, 1,1,2,3,3,3-hexachloro-
Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Boiling Point ]:
209.5±0.0 °C at 760 mmHg
[ Melting Point ]:
-73°C
[ Molecular Formula ]:
C3Cl6
[ Molecular Weight ]:
248.750
[ Flash Point ]:
69.9±23.3 °C
[ Exact Mass ]:
245.813110
[ LogP ]:
6.08
[ Vapour density ]:
8.3 (vs air)
[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.554
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UD0175000
- CHEMICAL NAME :
- Propene, hexachloro-
- CAS REGISTRY NUMBER :
- 1888-71-7
- BEILSTEIN REFERENCE NO. :
- 1766640
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C3-Cl6
- MOLECULAR WEIGHT :
- 248.73
- WISWESSER LINE NOTATION :
- GYGUYGXGGG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 425 ppm/30M
- TOXIC EFFECTS :
- Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea Liver - hepatitis (hepatocellular necrosis), diffuse
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 uL/kg
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 ppm/30M
- TOXIC EFFECTS :
- Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 85 ppm/30M
- TOXIC EFFECTS :
- Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 15 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,1,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6277 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H332-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R23;R36/37/38
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3382 6.1/PG 1
[ WGK Germany ]:
3
[ RTECS ]:
UD0175000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2903299090
Synthetic Route
Customs
[ HS Code ]: 2903299090
[ Summary ]:
2903299090 other unsaturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
Mutat. Res. 170(1-2) , 1-9, (1986)
In the presence of S9 mix all allylic chloropropenes tested exert considerable indirect mutagenic activity which is most pronounced for 1,2,3-trichloropropene. Lower as well as higher chlorinated deri...