2’-β-C-Ethynylcytidine

Names

[ Name ]:
2’-β-C-Ethynylcytidine

[Synonym ]:
Cytidine, 2'-C-ethynyl-
2'-C-Ethynylcytidine

Biological Activity

[Description]:

2’-β-C-Ethynylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
536.4±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₃N₃O₅

[ Molecular Weight ]:
267.24

[ Flash Point ]:
278.2±32.9 °C

[ Exact Mass ]:
267.085510

[ LogP ]:
0.10

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.677

2’-β-C-Ethynylcytidine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds