2'-C-Ethynyluridine

Names

[ Name ]:
2'-C-Ethynyluridine

[Synonym ]:
2'-C-Ethynyluridine
Uridine, 2'-C-ethynyl-

Biological Activity

[Description]:

2'-C-Ethynyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Molecular Formula ]:
C₁₁H₁₂N₂O₆

[ Molecular Weight ]:
268.22

[ Exact Mass ]:
268.069550

[ LogP ]:
0.05

[ Index of Refraction ]:
1.680

2'-C-Ethynyluridine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds