(1R, 3S, 4R)-ent-Entecavir

Names

[ Name ]:
(1R, 3S, 4R)-ent-Entecavir

[Synonym ]:
2-amino-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-9H-purin-6-ol
SC1449
6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-
2-Amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-Purin-6-one
2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one
2-Amino-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one
Entecavir Impurity 3

Biological Activity

[Description]:

(1R,3S,4R)-ent-Entecavir ((1R,3S,4R)-ent-BMS200475; (1R,3S,4R)-ent-SQ34676) can be used to synthesize PROTAC targets to degrade deoxyribonucleic acid (DNA) polymerase[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. SU, Xiang dong, et al. Compound for degrading deoxyribonucleic acid (dna) polymerase, and use thereof. WO2022156764A1.

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Molecular Formula ]:
C₁₂H₁₅N₅O₃

[ Molecular Weight ]:
277.279

[ Exact Mass ]:
277.117493

[ PSA ]:
130.05000

[ LogP ]:
-0.96

[ Index of Refraction ]:
1.837

Related Compounds

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