GRP78-IN-2

Names

[ CAS No. ]:
1882875-63-9

[ Name ]:
GRP78-IN-2

Biological Activity

[Description]:

GRP78-IN-2 (Compound FL5) is a GRP78 (Glucose Regulated Protein 78 kDa) inhibitor. GRP78-IN-2 preferentially targeting cell surface GRP78 and shows potent antiangiogenic and anticancer activities without affecting other normal cells[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> HSP
Signaling Pathways >> Cell Cycle/DNA Damage >> HSP

[References]

[1]. Qiao Y, et al. Discovery of small molecules targeting GRP78 for antiangiogenic and anticancer therapy. Eur J Med Chem. 2020 May 1;193:112228.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H29NO6

[ Molecular Weight ]:
487.54

Related Compounds