arachidonoyl coenzyme a (c20:4) lithium salt

Names

[ Name ]:
arachidonoyl coenzyme a (c20:4) lithium salt

[Synonym ]:
Arachidonoyl coenzyme A lithium salt
Arachidonoyl coenzyme A lithium salt

Biological Activity

[Description]:

Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vivo]

Arachidonoyl coenzyme A lithium is different of its synthetic activity in different regions, with higher synthesis in the homogenate and microsomes than in the cerebellum and brainstem while lower synthesis in the synaptic plasma membrane, and is unaltered in bicuculline-induced status epilepticus in male Wistar rats[1].

[References]

[1]. T S Reddy, et al. Synthesis of arachidonoyl coenzyme A and docosahexaenoyl coenzyme A in synaptic plasma membranes of cerebrum and microsomes of cerebrum, cerebellum, and brain stem of rat brain. J Neurosci Res. 1985;13(3):381-90.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₁H₆₅LiN₇O₁₇P₃S

[ Molecular Weight ]:
1059.92000

[ Exact Mass ]:
1059.35000

[ PSA ]:
428.17000

[ LogP ]:
6.94470

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Identification of glycine N-acyltransferase-like 2 (GLYATL2) as a transferase that produces N-acyl glycines in humans.

FASEB J. 24 , 2795-2803, (2010)

The discovery of glycine conjugates of long-chain fatty acids (N-acyl glycines) in the brain and other non-neuronal tissues has led to the identification of an emerging class of bioactive lipids. The ...

CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase.

J. Lipid Res. 51 , 709-719, (2010)

Mutations in human CGI-58/ABHD5 cause Chanarin-Dorfman syndrome (CDS), characterized by excessive storage of triacylglycerol in tissues. CGI-58 is an alpha/beta-hydrolase fold enzyme expressed in all ...

Arachidonic acid stimulates extracellular Ca(2+) entry in rat pancreatic beta cells via activation of the noncapacitative arachidonate-regulated Ca(2+) (ARC) channels.

Cell Calcium 47 , 77-83, (2010)

Arachidonic acid (AA) is generated in the pancreatic islets during glucose stimulation. We investigated whether AA activated extracellular Ca(2+) entry in rat pancreatic beta cells via a pathway that ...

Related Compounds

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