Oleoyl coenzyme A lithium salt

Names

[ Name ]:
Oleoyl coenzyme A lithium salt

Biological Activity

[Description]:

Oleoyl coenzyme A (Oleoyl-CoA) lithium is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A lithium has a role as an Escherichia coli metabolite and a mouse metabolite[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Oleoyl coenzyme A (1 μM) can activate sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 in Xenopus oocytes[2].

[References]

[1]. Regina Ensenauer, et al. Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids. J Biol Chem. 2005 Sep 16;280(37):32309-16.

[2]. F M Gribble, et al. Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA. J Biol Chem. 1998 Oct 9;273(41):26383-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₉H₆₄Li₄N₇O₁₇P₃S

[ Molecular Weight ]:
1055.71000

[ Exact Mass ]:
1055.39000

[ PSA ]:
436.66000

[ LogP ]:
7.58540

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Glycosomal ABC transporters of Trypanosoma brucei: characterisation of their expression, topology and substrate specificity.

Int. J. Parasitol. 41 , 429-438, (2011)

Metabolism in trypanosomatids is compartmentalised with major pathways, notably glycolysis, present in peroxisome-like organelles called glycosomes. To date, little information is available about the ...

Acyl-coenzyme A:cholesterol acyltransferases.

Am. J. Physiol. Endocrinol. Metab. 297 , E1-9, (2009)

The enzymes acyl-coenzyme A (CoA):cholesterol acyltransferases (ACATs) are membrane-bound proteins that utilize long-chain fatty acyl-CoA and cholesterol as substrates to form cholesteryl esters. In m...

Purification of recombinant acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) from H293 cells and binding studies between the enzyme and substrates using difference intrinsic fluorescence spectroscopy.

Biochemistry 49 , 9957-9963, (2010)

Acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) is a membrane-bound enzyme utilizing long-chain fatty acyl-coenzyme A and cholesterol to form cholesteryl esters and coenzyme A. Previously, we ha...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.