1,3,6,8-Tetrahydroxynaphthalene

Names

[ Name ]:
1,3,6,8-Tetrahydroxynaphthalene

[Synonym ]:
2,4,5,7-tetrahydroxynaphthalene
1,3,6,8-Tetrahydroxynaphthalene
naphthalene-1,3,6,8-tetraol
1,3,6,8-Naphthalenetetrol
tetrahydroxynaphthalene
TETRAHYD-CPD
1,3,6,8-Tetrahydroxy-naphthalin

Biological Activity

[Description]:

1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an indispensable precursor to DHN (1,8-Dihydroxynaphthalene) melanin and is an unique symmetrical compound of polyketide origin[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

1,3,6,8-tetrahydroxynaphthalene (T4HN), an early precursor in the pentaketide pathway, is believed to be produced directly from malonyl-CoA and acetyl-CoA by type-1 polyketide synthases (PKSs)[2].

Chemical & Physical Properties

[ Density]:
1.638g/cm3

[ Boiling Point ]:
407.1ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₈O₄

[ Molecular Weight ]:
192.16800

[ Flash Point ]:
208.9ºC

[ Exact Mass ]:
192.04200

[ PSA ]:
80.92000

[ LogP ]:
1.66220

[ Vapour Pressure ]:
3.29E-07mmHg at 25°C

[ Index of Refraction ]:
1.832

[ Storage condition ]:
2-8°C

Safety Information

[ HS Code ]:
2907299090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2907299090

[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%