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R 715

Names

[ CAS No. ]:
185052-09-9

[ Name ]:
R 715

Biological Activity

[Description]:

R715 is a selective bradykinin B1 receptor antagonist. R715 significantly attenuates the hyperalgesic effect developed in Streptozotocin(HY-13753)-diabetic mice[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> GPCR/G Protein >> Bradykinin Receptor

[References]

[1]. Gabra BH, et al. Beneficial effect of chronic treatment with the selective bradykinin B1 receptor antagonists, R-715 and R-954, in attenuating streptozotocin-diabetic thermal hyperalgesia in mice. Peptides. 2003;24(8):1131-1139.  

Chemical & Physical Properties

[ Molecular Formula ]:
C57H81N13O12

[ Molecular Weight ]:
1140.33000

[ Exact Mass ]:
1139.61000

[ PSA ]:
389.77000

[ LogP ]:
3.67050


Related Compounds

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