Tivanisiran

Names

[ Name ]:
Tivanisiran

Biological Activity

[Description]:

Tivanisiran (SYL1001) is a siRNA used for the study of dry eye disease. Tivanisiran was designed to silence transient receptor potential vanilloid 1 (TRPV1)[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Neurological Disease

[In Vitro]

In vitro transfection of tivanisiran was shown to produce a 50-60% decrease in TRPV1 mRNA levels[1][2].

[References]

[1]. Anne-Marie Bleau, et al. Development of tivanisiran, a topical siRNA designed to

[2]. Javier Moreno-Montañés, et al. Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018 Apr;27(4):421-426.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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