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m-PEG6-Amine

Names

[ CAS No. ]:
184357-46-8

[ Name ]:
m-PEG6-Amine

[Synonym ]:
3,6,9,12,15,18-HEXAOXANONADECAN-1-AMINE
1-amino-3,6,9,12,15,18-hexaoxanonadecane
methyletherhexaethyleneglycol amine

Biological Activity

[Description]:

m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.

Chemical & Physical Properties

[ Density]:
1.036

[ Molecular Formula ]:
C13H29NO6

[ Molecular Weight ]:
295.37200

[ Exact Mass ]:
295.19900

[ PSA ]:
81.40000

[ LogP ]:
0.37480

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Precursor & DownStream


Related Compounds