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MK-6240

Names

[ CAS No. ]:
1841078-87-2

[ Name ]:
MK-6240

Biological Activity

[Description]:

MK-6240 is a positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs), exhibiting high specificity and selectivity for binding to NFTs.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[Target]

Ki: NFT[1].


[References]

[1]. Walji AM, et al. Discovery of 6-(Fluoro-(18)F)-3- (1H-pyrrolo [2,3-c]pyridin-1-yl) isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs). J Med Chem. 2016 May 26;59(10):4778-89.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H11FN4

[ Molecular Weight ]:
278.28

[ Storage condition ]:
2-8℃

Related Compounds