<Suppliers Price>

Biotin-β-Amyloid (1-40)

Names

[ CAS No. ]:
183906-14-1

[ Name ]:
Biotin-β-Amyloid (1-40)

[Synonym ]:
1,3-Dioxolo[4,5-g]quinolin-6(5H)-one, 7-[[(2-phenylethyl)[[1-[(tetrahydro-2-furanyl)methyl]-1H-tetrazol-5-yl]methyl]amino]methyl]-
7-{[(2-Phenylethyl){[1-(tetrahydro-2-furanylmethyl)-1H-tetrazol-5-yl]methyl}amino]methyl}[1,3]dioxolo[4,5-g]quinolin-6(5H)-one

Biological Activity

[Description]:

Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[In Vitro]

β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease. It is the major component of senile plaque amyloids, are physiological peptides present in the brain, cerebrospinal fluid (CSF) and plasma[1]. Biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. Biotin can be used for qualitative and quantitative detection, labelling or immobilisation.

[References]

[1]. Mikio Shoji, et al. Cerebrospinal fluid Abeta40 and Abeta42: natural course and clinical usefulness. Front Biosci. 2002 Apr 1;7:d997-1006.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
748.0±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H28N6O4

[ Molecular Weight ]:
488.538

[ Flash Point ]:
406.2±32.9 °C

[ Exact Mass ]:
488.217194

[ LogP ]:
3.40

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.715

Related Compounds