β Amyloid(28-35) human

β Amyloid(28-35) human is a β-amyloid peptide (Abeta), a lipid-induced amyloid core fragment. β Amyloid oligomers are neurotoxic, and β Amyloid(28-35) human can interact with neuronal membranes, regulate secondary structure and neurotoxicity, and cause Alzheimer's disease. β Amyloid(28-35) human has anisotropic effects on the acidic phospholipid DPH, resulting in enhanced internal fluidity of lipid membrane bilayers[1].

Research Areas >> Neurological Disease

[1]. Nagarajan S, et al. Lipid-induced conformational transition of the amyloid core fragment Abeta(28-35) and its A30G and A30I mutants. FEBS J. 2008 May;275(10):2415-27.