2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine

Names

[ Name ]:
2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine

[Synonym ]:
Cytidine, N-benzoyl-2'-deoxy-2'-fluoro-5-methyl-
N-Benzoyl-2'-deoxy-2'-fluoro-5-methylcytidine

Biological Activity

[Description]:

2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₁₇H₁₈FN₃O₅

[ Molecular Weight ]:
363.34

[ Exact Mass ]:
363.123047

[ LogP ]:
0.90

[ Index of Refraction ]:
1.657