hTrkA-IN-1

Names

[ Name ]:
hTrkA-IN-1

Biological Activity

[Description]:

hTrkA-IN-1 is a potent and orally active inhibitor of TrkA kinase with an IC50 of 1.3 nM, compound 2. extracted from patent WO2015175788. hTrkA-IN-1 can be used for the study of inflammatory disease, such as prostatitis, pelvic, et al[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor

[References]

[1]. Shelley Allen, et al. 1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor. Patent WO2015175788A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₂FN₇O₂

[ Molecular Weight ]:
529.61

Related Compounds

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