HN37

Names

[ CAS No. ]:
1821222-10-9

[ Name ]:
HN37

Biological Activity

[Description]:

HN37 as a potent and chemically stable antiepileptic drug candidate, with an EC50 of 37 nM for KCNQ2[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[In Vitro]

HN37 is a potent neuronal Kv7 activator with a subtype selectivity similar to RTG[1].

[References]

[1]. Yang-Ming Zhang, et al. Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate. J Med Chem. 2021 May 13;64(9):5816-5837.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₁FN₂O₂

[ Molecular Weight ]:
340.39

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.