1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Names

[ Name ]:
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

[Synonym ]:
UNII:U86ZGC74V5
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Ethanaminium, 2-[[[(2R)-2,3-bis[(1-oxotetradecyl)oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
Ethanaminium, 2-[[[2,3-bis[(1-oxotetradecyl)oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine
1,2-Dimyristoyl-sn-glycero-3-phosphocholi
(2R)-2,3-Bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
(R)-2,3-Bis(tetradecanoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate
L-β,γ-Dimyristoyl-α-lecithin
dimyristoylphosphatidyl choline
MFCD00036901
1,2-di-O-myristoyl-sn-glycero-3-phosphocholine
EINECS 242-085-9
DMPC
2,3-Bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
1,2-ditetradecanoyl-sn-glycero-3-phosphocholine DMPC

Biological Activity

[Description]:

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine is used for the study of lipid monolayers and bilayers[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Iwona Budziak, et al. Effect of polyols on the DMPC lipid monolayers and bilayers. Biochim Biophys Acta Biomembr. 2018 Nov;1860(11):2166-2174.

Chemical & Physical Properties

[ Boiling Point ]:
> 300ºC

[ Melting Point ]:
130ºC to 139ºC

[ Molecular Formula ]:
C₃₆H₇₂NO₈P

[ Molecular Weight ]:
677.932

[ Exact Mass ]:
677.499573

[ PSA ]:
121.00000

[ LogP ]:
8.75

[ Storage condition ]:
−20°C

[ Stability ]:
Stable, but heat sensitive - store at -20 C. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2923900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Investigating the role of GXXXG motifs in helical folding and self-association of plasticins, Gly/Leu-rich antimicrobial peptides.

Biophys. Chem. 196 , 40-52, (2014)

Plasticins (PTC) are dermaseptin-related antimicrobial peptides characterized by a large number of leucine and glycine residues arranged in GXXXG motifs that are often described to promote helix assoc...

Comparison of [corrected] actin- and glass-supported phospholipid bilayer diffusion coefficients.

Biophys. J. 108(8) , 1946-53, (2015)

The formation of biomimetic lipid membranes has the potential to provide insights into cellular lipid membrane dynamics. The construction of such membranes necessitates not only the utilization of app...

Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78.

Biochim. Biophys. Acta 1848(5) , 1139-46, (2015)

Antimicrobial peptides (AMPs) are a class of broad-spectrum antibiotics known by their ability to disrupt bacterial membranes and their low tendency to induce bacterial resistance, arising as excellen...