NM-3

Names

[ Name ]:
NM-3

[Synonym ]:
NM 3
NM 3 (isocoumarin)
2-(8-hydroxy-6-methoxy-1-oxo-1H-isochromen-3-yl)-propionic acid
2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic Acid
isocoumarin NM-3

Biological Activity

[Description]:

NM-3 is an isocoumarin with antiarthritic and antiangiogenic effects. NM-3 is an orally active antiangiogenic agent with low toxicity[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. T Nakashima, et al. Inhibition of angiogenesis by a new isocoumarin, NM-3. J Antibiot (Tokyo). 1999 Apr;52(4):426-8.

Chemical & Physical Properties

[ Density]:
1.434g/cm3

[ Boiling Point ]:
542.4ºC at 760mmHg

[ Molecular Formula ]:
C₁₃H₁₂O₆

[ Molecular Weight ]:
264.23100

[ Flash Point ]:
212.5ºC

[ Exact Mass ]:
264.06300

[ PSA ]:
96.97000

[ LogP ]:
1.69530

[ Vapour Pressure ]:
1.35E-12mmHg at 25°C

[ Index of Refraction ]:
1.608

Related Compounds

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