181427-78-1

181427-78-1 structure
181427-78-1 structure
  • Name: NM-3
  • Chemical Name: 2-(8-hydroxy-6-methoxy-1-oxoisochromen-3-yl)propanoic acid
  • CAS Number: 181427-78-1
  • Molecular Formula: C13H12O6
  • Molecular Weight: 264.23100
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2016-08-12 07:09:58
  • Modify Date: 2025-08-29 11:16:23
  • NM-3 is an isocoumarin with antiarthritic and antiangiogenic effects. NM-3 is an orally active antiangiogenic agent with low toxicity[1].

Name 2-(8-hydroxy-6-methoxy-1-oxoisochromen-3-yl)propanoic acid
Synonyms NM 3
NM 3 (isocoumarin)
2-(8-hydroxy-6-methoxy-1-oxo-1H-isochromen-3-yl)-propionic acid
2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic Acid
isocoumarin NM-3
Description NM-3 is an isocoumarin with antiarthritic and antiangiogenic effects. NM-3 is an orally active antiangiogenic agent with low toxicity[1].
Related Catalog
References

[1]. T Nakashima, et al. Inhibition of angiogenesis by a new isocoumarin, NM-3. J Antibiot (Tokyo). 1999 Apr;52(4):426-8.  

Density 1.434g/cm3
Boiling Point 542.4ºC at 760mmHg
Molecular Formula C13H12O6
Molecular Weight 264.23100
Flash Point 212.5ºC
Exact Mass 264.06300
PSA 96.97000
LogP 1.69530
Vapour Pressure 1.35E-12mmHg at 25°C
Index of Refraction 1.608
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