Fazamorexant

Names

[ CAS No. ]:
1808918-69-5

[ Name ]:
Fazamorexant

Biological Activity

[Description]:

Fazamorexant (YZJ-1139) is a potent orexin receptor antagonist. Fazamorexant can be used for insomnia research[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor)
Research Areas >> Neurological Disease

[References]

[1]. Zhang Y, et al. Asymmetric Synthesis of Nortropanes via Rh-Catalyzed Allylic Arylation. ACS Catal. 2022 Aug 5;12(15):8995-9002.  

[2]. Zhenya Zeng, et al. Development of a Scalable Route with Efficient Stereoisomer Control to YZJ-1139, an Orexin Receptor Antagonist. Org. Process Res. Dev. 2022, 26, 2, 447-457.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H25FN4O2

[ Molecular Weight ]:
432.49

Related Compounds