3’-β-C-Ethynyluridine

Names

[ Name ]:
3’-β-C-Ethynyluridine

[Synonym ]:
PJ-272
EUrd
3-C-Ethynyl-uridine
Uridine,3'-C-ethynyl

Biological Activity

[Description]:

3’-β-C-Ethynyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

[2]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.

Chemical & Physical Properties

[ Density]:
1.67g/cm3

[ Molecular Formula ]:
C₁₁H₁₂N₂O₆

[ Molecular Weight ]:
268.22

[ Exact Mass ]:
268.07000

[ PSA ]:
125.04000

[ Index of Refraction ]:
1.68

Synthetic Route

Click to get detail synthetic route

Related Compounds

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