HKSOX-1r

Names

[ Name ]:
HKSOX-1r

Biological Activity

[Description]:

HKSOX-1r is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r exhibits excellent selectivity and sensitivity towards superoxide anion radical[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

HKSOX-1r (2 μM; 30 min) detects mitochondrial respiratory inhibitor-induced O2•- formation in a highly sensitive and rapid manner in HCT116, BV-2 and RAW264.7 cells[1].

[In Vivo]

HKSOX-1r (10 μM; 20 min) detects distinct fluorescence distribution in zebrafish embryos are subjected to challenge of PMA or Antimycin A[1].

[References]

[1]. Hu JJ, et, al. Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo. J Am Chem Soc. 2015 Jun 3;137(21):6837-43.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₁₅F₁₀NO₁₄S₂

[ Molecular Weight ]:
855.54

Related Compounds

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