ML230

Names

[ Name ]:
ML230

Biological Activity

[Description]:

ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

EC50: ABCG2 (0.13 μM)[1]

[References]

[1]. Strouse JJ, et al. Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2. Probe Reports from the NIH Molecular Libraries Program. November 30, 2010.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₁N₅O₃

[ Molecular Weight ]:
439.47

[ Storage condition ]:
2-8℃

Related Compounds

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