1776055-05-0

1776055-05-0 structure

Name: ML230
Chemical Name: ML230
CAS Number: 1776055-05-0
Molecular Formula: C₂₅H₂₁N₅O₃
Molecular Weight: 439.47
Catalog: Research Areas Cancer
Create Date: 2019-06-30 15:47:15
Modify Date: 2024-01-05 17:03:01
ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1].

Name	ML230

Description	ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	EC50: ABCG2 (0.13 μM)[1]
References	[1]. Strouse JJ, et al. Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2. Probe Reports from the NIH Molecular Libraries Program. November 30, 2010.