Cyprodinil-d5

Names

[ Name ]:
Cyprodinil-d5

Biological Activity

[Description]:

Cyprodinil-d5is the deuterium labeledCyprodinil(HY-116214)[1]. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 μM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 μM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 μM)[2].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₀D₅N₃

[ Molecular Weight ]:
230.32

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H317-H319-H410

[ Precautionary Statements ]:
P273-P280-P333 + P313-P337 + P313-P391-P501

[ RIDADR ]:
UN 3077 9 / PGIII

Related Compounds

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