Nidufexor

Names

[ Name ]:
Nidufexor

[Synonym ]:
Benzoic acid, 4-[[[(8-chloro-1,4-dihydro-1-methyl[1]benzopyrano[4,3-c]pyrazol-3-yl)carbonyl](phenylmethyl)amino]methyl]-
4-({Benzyl[(8-chloro-1-methyl-1,4-dihydrochromeno[4,3-c]pyrazol-3-yl)carbonyl]amino}methyl)benzoic acid

Biological Activity

[Description]:

Nidufexor is a farnesoid X receptor (FXR) agonist[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> FXR

Research Areas >> Others

[Target]

FXR[1]

[References]

[1]. Proposed INN: List 118. WHO Drug Information, Vol. 31, No. 4, 2017.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
781.1±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₂₂ClN₃O₄

[ Molecular Weight ]:
487.93

[ Flash Point ]:
426.2±32.9 °C

[ Exact Mass ]:
487.129883

[ LogP ]:
3.72

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.671

[ Storage condition ]:
2-8℃

Related Compounds

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