H-Leu-D-Leu-OH

Names

[ CAS No. ]:
17665-02-0

[ Name ]:
H-Leu-D-Leu-OH

[Synonym ]:
L-Leucyl-D-leucine Dihydrate
MFCD00066071
H-LEU-D-LEU-OH

Biological Activity

[Description]:

(R)-2-((S)-2-amino-4-methylpentanamido)-4-methylpentanoic acid dihydrate is a leucine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.051g/cm3

[ Boiling Point ]:
432.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₂₄N₂O₃

[ Molecular Weight ]:
244.33100

[ Flash Point ]:
215.5ºC

[ Exact Mass ]:
244.17900

[ PSA ]:
92.42000

[ LogP ]:
2.06650

[ Vapour Pressure ]:
1.07E-08mmHg at 25°C

[ Index of Refraction ]:
1.481

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...

Rapid analysis of peptides and amino acids by CE-ESI-MS using chemically modified fused-silica capillaries.

Electrophoresis 30 , 2273-2279, (2009)

The objective of this study was to prepare a coated capillary to achieve rapid analysis of peptides and amino acids (AAs) by CE-ESI-MS. The coated capillary was prepared by chemical modification of th...

The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site.

Mol. Biol. Cell 18 , 1887-1896, (2007)

The clathrin adaptors AP-1 and AP-2 bind cargo proteins via two types of motifs: tyrosine-based Yxx phi and dileucine-based [DE]XXXL[LI]. Although it is well established that Yxx phi motifs bind to th...