[Ala28]-β Amyloid(25-35)

Names

[ Name ]:
[Ala28]-β Amyloid(25-35)

Biological Activity

[Description]:

[Ala28]-β Amyloid(25-35) (β(25-35)KA) is an electrically neutral mutant peptide of Aβ(25-35) that accelerates the aggregation of Firefly Luciferase[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. T Konno. Amyloid-induced aggregation and precipitation of soluble proteins: an electrostatic contribution of the Alzheimer's beta(25-35) amyloid fibril. Biochemistry. 2001 Feb 20;40(7):2148-54.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₂H₇₄N₁₂O₁₄S

[ Molecular Weight ]:
1003.17

[ Appearance of Characters ]:
lyophilized

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Folding and membrane insertion of amyloid-beta (25-35) peptide and its mutants: implications for aggregation and neurotoxicity.

Proteins 78 , 1909-1925, (2010)

The mechanisms of interfacial folding and membrane insertion of the Alzheimer's amyloid-beta fragment Abeta(25-35) and its less toxic mutant, N27A-Abeta(25-35) and more toxic mutant, M35A-Abeta(25-35)...

Related Compounds

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