Z-Gly-ONp

Names

[ Name ]:
Z-Gly-ONp

[Synonym ]:
(4-nitrophenyl) 2-(phenylmethoxycarbonylamino)acetate
Glycine, N-[(phenylmethoxy)carbonyl]-, 4-nitrophenyl ester
EINECS 217-097-2
CARBOBENZYLOXYGLYCINE 4-NITROPHENYL ESTER
MFCD00024663
N-Cbz-glycine 4-Nitrophenyl Ester
4-Nitrophenyl 2-(((benzyloxy)carbonyl)amino)acetate
4-Nitrophenyl N-[(benzyloxy)carbonyl]glycinate
N-Carbobenzoxyglycine 4-Nitrophenyl Ester
N-benzyloxycarbonylglycine 4-nitrophenyl ester
Z-Gly-Onp

Biological Activity

[Description]:

4-Nitrophenyl ((benzyloxy)carbonyl)glycinate is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
542.4±45.0 °C at 760 mmHg

[ Melting Point ]:
120-122ºC

[ Molecular Formula ]:
C₁₆H₁₄N₂O₆

[ Molecular Weight ]:
330.292

[ Flash Point ]:
281.8±28.7 °C

[ Exact Mass ]:
330.085175

[ PSA ]:
110.45000

[ LogP ]:
3.14

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.595

[ Storage condition ]:
-15°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB9139000

CHEMICAL NAME :: Glycine, N-carboxy-, N-benzyl ester, p-nitrophenyl ester

CAS REGISTRY NUMBER :: 1738-86-9

BEILSTEIN REFERENCE NO. :: 1916980

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C16-H14-N2-O6

MOLECULAR WEIGHT :: 330.32

WISWESSER LINE NOTATION :: WNR DOV1MVO1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 280 mg/kg

SEX/DURATION :: female 28 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 70,60,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravaginal

DOSE :: 280 mg/kg

SEX/DURATION :: female 28 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 70,60,1981

Safety Information

[ Hazard Codes ]:
Xi,N

[ Risk Phrases ]:
43-51

[ Safety Phrases ]:
53-36/37-61

[ RTECS ]:
MB9139000

[ HS Code ]:
2924299090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%