5-Nitro BAPTA tetramethyl ester

5-Nitro BAPTA tetramethyl ester is a calcium chelator. 5-Nitro BAPTA tetramethyl ester involves in the two-photon probe synthesis, and is used for real-time imaging of intracellular calcium ions, calcium waves monitoring at a depth of 100-300 μm in liver tissues for 1100-4000 s. 5-Nitro BAPTA tetramethyl ester, together with fluorescent compound 2-Me-substituted TM, can be used to form a red fluorescent probe (CaTM-2 AM)[1][2].

Research Areas >> Others

Signaling Pathways >> Others >> Others

[1]. Egawa T, et al. Red fluorescent probe for monitoring the dynamics of cytoplasmic calcium ions. Angew Chem Int Ed Engl. 2013 Apr 2;52(14):3874-7.

[2]. Cho Bong Rae, et al. Two-photon probe for real-time monitoring of intracellular calcium ions, method for preparing the probe and method for real-time monitoring of intracellular calcium ions using the probe: World Intellectual Property Organization, WO2009031734[P]. 2009-03-12.