Mosher's acid
Names
[ CAS No. ]:
17257-71-5
[ Name ]:
Mosher's acid
[Synonym ]:
(S)-(-)-α-Methoxy-α-(trifluoroMethyl)phenylacetic Acid [Optical Resolving]
Mosher's acid
MFCD00064200
Benzeneacetic acid, α-methoxy-α-(trifluoromethyl)-, (αS)-
mtpa
(S)-Mosher's Acid
(±)-Mosher's acid
a-Methoxy-a-(trifluoromethyl)phenylacetic Acid
(-)-Mosher's acid
UNII:E015GCC0MA
(−)-MTPA
(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid
(±)-MTPA
3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid
EINECS 241-292-1
(2S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid
α-methoxy-α-trifluoromethylphenylacetic acid
(S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid
(S)-(-)-MTPA
Benzeneacetic acid, α-methoxy-α-(trifluoromethyl)-
Methoxy (trifluoromethyl)phenylacetic acid
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
287.2±0.0 °C at 760 mmHg
[ Melting Point ]:
46-49ºC
[ Molecular Formula ]:
C10H9F3O3
[ Molecular Weight ]:
234.172
[ Flash Point ]:
134.2±27.3 °C
[ Exact Mass ]:
234.050385
[ PSA ]:
46.53000
[ LogP ]:
3.79
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.470
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2918990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918990090
[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho. Hokoku. (121) , 87-8, (2003)
Mosher ester analysis for the determination of absolute configuration of stereogenic (chiral) carbinol carbons.
Nat. Protoc. 2 , 2451-2458, (2007)
This protocol details the most commonly used nuclear magnetic resonance (NMR)-based method for deducing the configuration of otherwise unknown stereogenic, secondary carbinol (alcohol) centers (R1R2CH...
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion.Nat. Neurosci. 8(11) , 1481-9, (2005)
Drug addiction is increasingly viewed as the endpoint of a series of transitions from initial drug use--when a drug is voluntarily taken because it has reinforcing, often hedonic, effects--through los...